2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-15537
    Tilbroquinol
    		Inhibitor 98.02%
    Tilbroquinol is an orally active antiparasite agent, can be used in study of amoebiasis. tilbroquinol is also used against Vibrio cholera.
    Tilbroquinol
  • HY-B1177
    Crotamiton
    		Inhibitor
    Crotamiton is a drug that is used both as a scabicidal (for treating scabies) and as a general antipruritic.
    Crotamiton
  • HY-17599
    Piperazine citrate
    		≥98.0%
    Piperazine (1,4-Diazacyclohexane) citrate is a gamma-aminobutyric acid (GABA) agonist. Piperazine citrate is a vital building block and is an essential core in numerous marketed agents with diverse pharmacological activities.
    Piperazine citrate
  • HY-B1331
    Cyromazine
    		99.79%
    Cyromazine (CGA-72662) is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine works by affecting the nervous system of the immature larval stages of certain insects. Cyromazine reduced the number of germ cells by interfering with the Ecdysone (HY-N0179) signaling pathway. Cyromazine induces renal toxicity attenuated and restored by green tea extract in rats.
    Cyromazine
  • HY-B1036
    Decoquinate
    		Inhibitor 99.26%
    Decoquinate is an orally active, selective inhibitor of the mitochondrial bc1 complex, targeting Eimeria spp. sporozoites and first generation schizonts, and Plasmodium spp. Decoquinate inhibits electron transfer by competitively binding to the mitochondrial cytochrome b system, blocking the parasite's energy metabolism, thereby inhibiting its development and reproduction. Decoquinate has significant anticoccidial activity, preventing intestinal damage and improving host growth performance, and also has inhibitory effects on the liver and blood stages of Plasmodium. Decoquinate is mainly used in veterinary research to prevent and treat coccidiosis in ruminants and poultry.
    Decoquinate
  • HY-B1072
    Phenothrin
    		Inhibitor
    Phenothrin is a synthetic pyrethroid that kills adult fleas and ticks.
    Phenothrin
  • HY-W098348
    N-Methyltaurine
    		≥98.0%
    N-Methyltaurine is a taurine-derived metabolite with a minimum effective concentration of 10 μM for maintaining hamster sperm motility. N-Methyltaurine is the dominant osmolyte of Vespermum virulentum.
    N-Methyltaurine
  • HY-107483
    Cambendazole
    		98.83%
    Cambendazole is one of the most effective agents for the research of human strongyloidiasis and .
    Cambendazole
  • HY-123561
    MMV008138
    		Inhibitor 98.49%
    MMV008138 is a species-selective IspD (enzyme 2-C-methyl-d-erythritol 4-phosphate cytidylyltransferase)-targeting antimalarial agent, with an IC50 of 44 nM for PfIspD (P. falciparum IspD). MMV008138 inhibits the growth of P. falciparum Dd2 strain with an IC50 of 250 nM.
    MMV008138
  • HY-135811A
    Desethyl chloroquine diphosphate
    		Inhibitor 99.72%
    Desethyl chloroquine diphosphate is a major desethyl metabolite of Chloroquine. Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors (TLRs). Desethyl chloroquine diphosphate possesses antiplasmodic activity.
    Desethyl chloroquine diphosphate
  • HY-111759
    Jaspamycin
    		Inhibitor 98.60%
    Jaspamycin (7-CN-7-C-Ino) is a potent activator of PKA, binding to the R site (PKAR), with an EC50 of 6.5 nM and Kd of 8 nM in Trypanosoma brucei. Jaspamycin (7-CN-7-C-Ino) does not bind with purified human PKARIα. Anti-parasite activity.
    Jaspamycin
  • HY-156685
    EDI048
    		Inhibitor 99.86%
    EDI048 (compound 1.16) is an orally active Cryptosporidium PI4K inhibitor for the research of cryptosporidiosis.
    EDI048
  • HY-132170
    DSM502
    		Inhibitor 99.74%
    DSM502 is a pyrrole-based Dihydroorotate Dehydrogenase (DHODH) inhibitor. DSM502 exhibits nanomolar potency againsts Plasmodium DHODH and Plasmodium parasites, with no inhibition of mammalian DHODHs.
    DSM502
  • HY-127102
    GSK3494245
    		Inhibitor 98.56%
    GSK3494245 (DDD01305143) is a potent, orally active, and selective inhibitor of the chymotrypsin-like activity of the parasite proteasome binding in a site sandwiched between the β4 and β5 subunits (IC50=0.16 μM for WT L. donovani proteasomes). GSK3494245 moderately inhibits chymotrypsin-like activity of human proteasome (IC50: purified 26S=13 µM; enriched THP-1 extracts IC50=40µM). GSK3494245 exhibits attractive biological and biosafety properties.
    GSK3494245
  • HY-19364
    Ferroquine
    		Inhibitor 99.68%
    Ferroquine (Ferrochloroquine), a ferrocenyl analogue of Chloroquine, is an antimalarial agent. Ferroquine shows parasiticidal effect on Plasmodium by inducing oxidative stress and the subsequent destruction of the membrane.
    Ferroquine
  • HY-136330
    Oxazosulfyl
    		Inhibitor 99.66%
    Oxazosulfyl is a sulfyl insecticide with potent and cross-spectrum insecticidal activity. Oxazosulfyl inhibits sodium currents by binding to and stabilizing the slow-inactivated state of voltage-gated sodium channels, leading to insect paralysis. Oxazosulfyl's ability to block sodium channels is correlated with its insecticidal activity.
    Oxazosulfyl
  • HY-17373R
    Posaconazole (Standard)
    Posaconazole (Standard) is the analytical standard of Posaconazole. This product is intended for research and analytical applications. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity.
    Posaconazole (Standard)
  • HY-16779
    Fosravuconazole
    		Inhibitor 99.86%
    Fosravuconazole (BMS-379224), a proagent of Ravuconazole, is an orally active broad spectrum antifungal agent. Fosravuconazole can be used for candidiasis, onychomycosis and parasitemia research.
    Fosravuconazole
  • HY-135578
    Artelinic acid
    		Inhibitor 99.96%
    Artelinic acid, a derivative of Artemisinin, is an antimalarial agent for the treatment of multidrug resistant strains of Plasmodium falciparum. Artelinic acid can be administered by various routes of administration, including intravenous, intramuscular and oral routes.
    Artelinic acid
  • HY-W133894
    Cedar oil
    		Inhibitor
    Cedar oil is an essential oil that can be extracted from numerous types of conifers. Cedar oil possesses some pesticidal properties. As a food additive and preservative, cedarwood oil is a blend of organic chemicals classified as safe compounds by the FDA.
    Cedar oil
Parasite Isoform Comparison

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